Atsunori Nakao Selected Research

Hydrogen

10/2021	The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury.
4/2019	Hydrogen gas inhalation ameliorates lung injury after hemorrhagic shock and resuscitation.
1/2017	Inhaled hydrogen ameliorates endotoxin-induced bowel dysfunction.
10/2016	The Clinical Application of Hydrogen as a Medical Treatment.
1/2016	Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production.
10/2015	The effects of hydrogen gas inhalation during ex vivo lung perfusion on donor lungs obtained after cardiac death.
8/2015	Hydrogen inhalation protects against acute lung injury induced by hemorrhagic shock and resuscitation.
5/2013	Hydrogen gas reduces hyperoxic lung injury via the Nrf2 pathway in vivo.
12/2012	Hydrogen-supplemented drinking water protects cardiac allografts from inflammation-associated deterioration.
8/2012	A basic study on molecular hydrogen (H2) inhalation in acute cerebral ischemia patients for safety check with physiological parameters and measurement of blood H2 level.

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Atsunori Nakao Research Topics

Disease

32	Reperfusion Injury 01/2022 - 11/2002
18	Ischemia 01/2022 - 04/2004
17	Inflammation (Inflammations) 01/2017 - 04/2004
13	Wounds and Injuries (Trauma) 06/2022 - 08/2004
11	Lung Injury 10/2021 - 12/2005
11	Necrosis 10/2015 - 11/2004
10	Hemorrhage 01/2021 - 11/2004
8	Acute Lung Injury 04/2019 - 12/2005
7	Endotoxemia 01/2017 - 08/2009
6	Pneumonia (Pneumonitis) 10/2021 - 12/2005
6	Neoplasms (Cancer) 01/2021 - 07/2002
6	Ileus 01/2017 - 12/2006
6	Edema (Dropsy) 01/2014 - 08/2003
4	Heart Arrest (Cardiac Arrest) 06/2022 - 01/2017
4	Fibrosis (Cirrhosis) 10/2021 - 02/2006
4	Respiratory Insufficiency (Respiratory Failure) 01/2021 - 09/2014
4	Hypoxia (Hypoxemia) 01/2020 - 06/2008
4	Hemorrhagic Shock 04/2019 - 07/2010
4	Critical Illness (Critically Ill) 04/2017 - 03/2013
4	Sepsis (Septicemia) 01/2017 - 04/2005
4	Atrophy 01/2010 - 04/2002
3	Out-of-Hospital Cardiac Arrest 05/2022 - 01/2022
3	COVID-19 01/2022 - 01/2020
3	Poisoning 07/2021 - 01/2014
3	Brain Diseases (Brain Disorder) 01/2019 - 04/2017
3	Hyperplasia 04/2012 - 07/2005
3	Proteinuria 01/2010 - 02/2006
2	Shock 01/2021 - 03/2008
2	Stomach Ulcer (Gastric Ulcer) 01/2021 - 01/2016
2	Infections 01/2021 - 10/2014
2	Human Influenza (Influenza) 01/2021 - 09/2014
2	Anaphylaxis (Anaphylactic Shock) 01/2021 - 10/2018
2	Burns 12/2020 - 01/2019
2	Hypertension (High Blood Pressure) 11/2020 - 01/2020
2	Lactic Acidosis 10/2020 - 04/2013
2	Abdominal Pain (Pain, Abdominal) 01/2019 - 01/2019
2	Cardiac Arrhythmias (Arrythmia) 01/2019 - 10/2017
2	Disease Progression 01/2019 - 05/2014
2	Septic Shock (Toxic Shock Syndrome) 04/2017 - 02/2014
2	Lung Diseases (Lung Disease) 10/2015 - 05/2013
2	Infarction (Infarctions) 03/2014 - 01/2008

Drug/Important Bio-Agent (IBA)

24	Carbon MonoxideIBA 01/2022 - 10/2003
21	HydrogenIBA 10/2021 - 01/2010
10	Oxygen (Dioxygen)IBA 07/2021 - 01/2010
7	Alanine Transaminase (SGPT)IBA 08/2015 - 08/2005
7	Biliverdine (Biliverdin)IBA 12/2012 - 08/2004
6	LipopolysaccharidesIBA 01/2017 - 08/2009
6	SolutionsIBA 01/2016 - 12/2006
5	CytokinesIBA 01/2017 - 08/2009
5	Interleukin-6 (Interleukin 6)IBA 10/2015 - 04/2004
5	InterleukinsIBA 02/2015 - 08/2010
5	EndotoxinsIBA 01/2014 - 12/2005
5	Heme Oxygenase-1IBA 03/2008 - 08/2004
4	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 01/2010
4	Proteins (Proteins, Gene)FDA Link 01/2017 - 05/2009
4	AntioxidantsIBA 07/2016 - 03/2010
4	Aspartate Aminotransferases (Aspartate Transaminase)IBA 08/2015 - 08/2005
4	Interleukin-18 (Interleukin 18)IBA 08/2015 - 01/2014
4	HMGB1 Protein (HMG1)IBA 08/2009 - 04/2005
4	Heme (Haem)IBA 10/2008 - 02/2005
3	hydrogen rich salineIBA 11/2020 - 08/2010
3	Glucose (Dextrose)FDA LinkGeneric 10/2020 - 11/2012
3	NitrogenIBA 01/2017 - 01/2010
3	Messenger RNA (mRNA)IBA 01/2017 - 11/2004
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 01/2014 - 11/2004
3	Heme Oxygenase (Decyclizing) (Heme Oxygenase)IBA 05/2013 - 02/2005
3	CreatinineIBA 01/2010 - 02/2006
2	CollagenIBA 06/2022 - 02/2006
2	Phenobarbital (Luminal)FDA Link 01/2022 - 11/2020
2	Nicotine FDA Link 01/2021 - 12/2020
2	Transaminases (Aminotransferases)IBA 10/2020 - 01/2005
2	EnzymesIBA 10/2020 - 12/2005
2	Insulin (Novolin)FDA Link 10/2020 - 02/2015
2	Indicators and Reagents (Reagents)IBA 09/2020 - 07/2012
2	AnticoagulantsIBA 01/2020 - 04/2014
2	fibrin fragment D (D-dimer)IBA 01/2020 - 10/2017
2	Fluorouracil (Carac)FDA LinkGeneric 01/2018 - 07/2002
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2016 - 08/2009
2	Fish OilsIBA 03/2014 - 03/2013
2	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 01/2014 - 11/2004
2	Transcription Factors (Transcription Factor)IBA 09/2012 - 06/2006

Therapy/Procedure

13	Transplantation 01/2022 - 10/2003
13	Therapeutics 10/2021 - 05/2006
7	Resuscitation 01/2022 - 07/2010
4	Cardiopulmonary Resuscitation (CPR) 06/2022 - 01/2019
4	Laparotomy 10/2021 - 01/2016
4	Extracorporeal Membrane Oxygenation 01/2021 - 04/2014
4	Liver Transplantation 01/2019 - 08/2005
4	Artificial Respiration (Mechanical Ventilation) 10/2014 - 01/2010
4	Kidney Transplantation 07/2009 - 11/2004
3	Aftercare (After-Treatment) 01/2020 - 08/2008
3	Drug Therapy (Chemotherapy) 01/2018 - 07/2002
3	Critical Care (Surgical Intensive Care) 04/2017 - 05/2013
3	Heart Transplantation (Grafting, Heart) 07/2016 - 08/2009
3	Lung Transplantation 10/2015 - 08/2008
2	Personal Protective Equipment 01/2022 - 01/2020
2	Resuscitation Orders (Do Not Resuscitate Orders) 01/2022 - 01/2021
2	Surgical Amputation (Amputations) 03/2021 - 01/2017
2	Hyperbaric Oxygenation 11/2018 - 04/2018
2	Parenteral Nutrition 03/2014 - 03/2013